Treating bile acid synthesis disorders (BASDs) with CHOLBAM
Getting Started
CHOLBAM comes in 50-mg and 250-mg capsules. Your doctor will recommend a dose based on weight—typically 10 to 15 mg per kilogram. You might start with twice-daily doses as you adjust, then move to once daily. Your doctor will determine what works best for you.
Staying on Track
Your doctor will check liver function monthly for the first 3 months, then less frequently after that. If you're not seeing improvement after 3 months or symptoms get worse, your doctor may discuss next steps with you.
Day by Day
Taking CHOLBAM every day, as prescribed, helps your body produce the bile acids it needs for proper liver function and digestion. It's a long-term therapy, so the benefits build over time. When you stick with your routine, you're giving your body the support it needs.
Weight matters
Keep your doctor updated about weight changes, as they may need to adjust the dose. Don't adjust on your own.
As always, if you have any questions, talk with your doctor.
Taking CHOLBAM
Take CHOLBAM by mouth with food. Keep the capsules whole—don't crush or chew them.
Space it at least 1 hour before or 4 to 6 hours after bile acid binders or aluminum antacids.
Cholbie says—Don't worry, there are options if the capsules are hard to swallow!
Open the capsule and mix the granules with:
- 1 to 2 tablespoons of Infant formula or expressed breast milk for younger children
or
- 1 to 2 tablespoons of soft food like mashed potatoes, applesauce, pudding, or yogurt, which can help mask the taste
The contents of the capsule won't dissolve; there will still be fine granules once it's mixed. Use the mixture immediately.
Cholbie's tip: Don't mix CHOLBAM into your favorite meal!
If something tastes off, you don't want to lose a trusted meal. Work with your dietitian to find the best mixing strategy that protects your favorite foods.
How to receive CHOLBAM
Getting started on CHOLBAM is simple through Mirum Access Plus.
If you have any questions about Mirum Access Plus, contact us at: 1-855-MRM-4YOU (1-855-676-4968) Monday through Friday, 8:00 am to 8:00 pm ET, or download and sign the Mirum Access Plus Consent Form to sign up.
CHOLBAM may help when managing BASDs
