Why testing for BASD matters

Genetic testing can help accelerate care and treatment outcomes

Travere Therapeutics offers no-cost testing programs to help improve the diagnosis and understanding of a bile acid synthesis disorder (BASD).

Ask your doctor to order the Genetic Cholestasis Panel.

Genetic testing

Your doctor can diagnosis BASD through genetic testing, which identifies mutations in genes that can cause cholestasis—a condition where bile flow is reduced or stopped. Your doctor can order the Genetic Cholestasis Panel by visiting testcholestasis.com.

If you qualify, you can receive this no-cost test, through your doctor, to help determine if your child has BASD. Talk to your doctor about genetic testing for cholestasis today.

View Test Information

Atypical bile acid testing

If your child has been diagnosed with BASD, your child’s doctor can run a urine test called an atypical bile acid test. Atypical bile acid tests are less common but can give your doctor more information about the health of your child’s liver. This test is easy to use and detects the presence of atypical bile acids, which can be harmful to the liver and are associated with cholestasis and liver disease.

This testing program is a partnership between Travere Therapeutics and the Cincinnati Children’s Hospital Medical Center.

If you qualify, this test is available at no cost to you and can be ordered through your child’s doctor. Download the atypical bile acid test information and talk to your child’s doctor about running this important test.

Download Test Information
Travere Therapeutics and the Cincinnati Children's Hospital have partnered on a atypical bile acid testing program.

WHAT IS CHOLBAM® (cholic acid) capsules?

CHOLBAM is a prescription medicine. It is a bile acid used for

  • Treatment of bile acid synthesis disorders (malfunction in the production of bile acid in the liver) due to a lack of a single enzyme responsible for bile acid production
  • Treatment (in addition to other treatments) of peroxisomal disorders (a loss of function in important parts of the cell), including Zellweger spectrum disorders, in patients who show signs or symptoms of liver disease, pale stools due to too much fat, or problems resulting from not absorbing certain vitamins (A, D, E, K)

The safety and effectiveness of CHOLBAM on symptoms outside of the liver have not been studied.


CHOLBAM may not be right for you. Before taking CHOLBAM, tell your doctor about:

  • All health conditions you may have and any medications you may be taking
  • If you are pregnant or plan to become pregnant. Women who become pregnant during CHOLBAM treatment are encouraged to call 1-844-202-6262
  • If you are breastfeeding or plan to breastfeed


What are the possible side effects of CHOLBAM?

  • Serious Side Effects: You will need to undergo laboratory testing periodically while on treatment to assess liver function. CHOLBAM may worsen liver function. Tell your doctor right away if you experience symptoms associated with worsening of liver function (e.g., skin or the whites of eyes turn yellow, urine turns dark or brown [tea colored], pain on the right side of stomach, bleeding or bruising occurs more easily than normal, or increased lethargy). Your doctor will decide if you need to discontinue treatment with CHOLBAM.
  • Most Common Side Effects: Diarrhea, acid reflux that damages the lining of the esophagus, discomfort and fatigue, yellowing of skin or eyes, skin lesion, nausea, abdominal pain, formation of growths in the intestinal tract, urinary tract infection, nerve damage causing change in sensation in extremities.

These are not all the possible side effects of CHOLBAM. Tell your doctor if you have any side effect that bothers you or that does not go away.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Travere Therapeutics at 1-877-659-5518.

Please see accompanying full Prescribing Information for additional Important Safety Information.